Non-Alcoholic Fatty Liver Disease: A Practical Guide / Edition 1 available in Hardcover, eBook
Non-Alcoholic Fatty Liver Disease: A Practical Guide / Edition 1
- ISBN-10:
- 0470673176
- ISBN-13:
- 9780470673171
- Pub. Date:
- 04/29/2013
- Publisher:
- Wiley
Non-Alcoholic Fatty Liver Disease: A Practical Guide / Edition 1
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Product Details
ISBN-13: | 9780470673171 |
---|---|
Publisher: | Wiley |
Publication date: | 04/29/2013 |
Pages: | 328 |
Product dimensions: | 6.80(w) x 9.60(h) x 1.20(d) |
About the Author
Arthur McCullough, Department Chair of Gastroenterology and Hepatology, Cleveland Clinic, USAArthur McCullough, MD, is Department Chair of Gastroenterology and Hepatology and a Staff Physician in the Department of Pathobiology and Transplantation Center at Cleveland Clinic. He was appointed in 2006. He attended medical school at SUNY Health Science Center at University Hospital of Syracuse, N.Y. He completed his internship and residency at Cleveland Clinic and a fellowship at Mayo Clinic in Rochester, Minn.He is one of the most senior hepatologists in the United States and is the current President of the American Association for the Study of Liver Diseases. Other significant achievements are: Best Doctor's in America: "Midwest Region" annually from 1996-2008; Chair of the NIH-funded Clinical Research Network on Fatty Liver Disease (federal funding); NIH Grant on Omega 3 Fatty Acids in Diabetes (federal funding); New Novel Agents for Hepatitis C Patients who failed to respond to previous therapy (non-federal funding)
Christopher Day, Pro-Vice-Chancellor for the Faculty of Medical Sciences, Professor of Liver Medicine and Consultant Hepatologist, School of Clinical Medical Sciences, Newcastle University, UKChris Day qualified from Cambridge University in 1983 and subsequently trained in General Medicine and Hepatology at Newcastle, becoming Consultant Hepatologist in the Liver Unit at Newcastle’s Freeman Hospital in 1994 and Professor of Liver Medicine at University of Newcastle University in 2000. He was formerly Head of the School of Clinical Medical Sciences at the University and since April 2008 has been Pro-Vice-Chancellor of the Faculty of Medical Sciences. Professor Day's research interests focus largely on fatty liver disease related both to obesity and to alcohol, with additional interests in drug-induced liver injury and liver fibrosis. His work has been funded by the MRC and the Wellcome Trust and he is a former MRC Clinical Training Fellow and Clinician Scientist Fellow. In 1999 he was the Goulstonian Lecturer of the Royal College of Physicians and in 2000 was awarded the research gold medal of the British Society of Gastroenterology. He is a Fellow and Councillor of the Academy of Medical Sciences, an Executive Member of the Medical Schools Council and an NIHR Senior Investigator. He is also Chief Editor of the Journal of Hepatology, and is on both the Populations and Systems Medicine Board and the Translational Stem Cell Research Committee of the Medical Research Council.
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Table of Contents
List of Contributors, vii1 What is non-alcoholic fatty liver disease (NAFLD), and why is it important? 1 Geoffrey C. Farrell, Arthur J. McCullough, and Christopher P. Day
2 NAFLD in the community, 17 Leon A. Adams
3 Pathology of NAFLD, 27 Elizabeth M. Brunt and David E. Kleiner
4 The natural history of NAFLD, 37 Paul Angulo
5 Emerging concepts on the pathogenesis of non-alcoholic steatohepatitis (NASH), 46 Isabelle A. Leclercq
6 Diabetes and NAFLD: why is the connection important? 62 Elisabetta Bugianesi
7 NAFLD and cardiovascular risk factors: implications for vascular disease, 71 Giovanni Targher
8 A primary care perspective of fatty liver: diagnosis, management, prescribing, and when to refer, 84 Shivakumar Chitturi and Geoffrey C. Farrell
9 Imaging of NAFLD, 93 Takeshi Yokoo, An Tang, and Claude B. Sirlin
10 Non-invasive methods to determine the severity of NAFLD and NASH, 112 Vincent Wai-Sun Wong and Henry Lik-Yuen Chan
11 Fatigue, quality of life, and psychosocial issues for people with NAFLD, 122 Julia L. Newton and James Frith
12 Physical activity and cardiovascular fi tness in patients with NAFLD: clinical importance and therapeutic implications, 132 Ingrid J. Hickman, Graeme A. Macdonald, and Nuala M. Byrne
13 NAFLD, obesity, and bariatric surgery, 149 Philippe Mathurin
14 Genetic predisposition to NAFLD and NASH: implications for pathogenesis, diagnosis, prevention, and management, 157 Quentin M. Anstee, Ann K. Daly, and Christopher P. Day
15 NAFLD in children, 171 Ariel E. Feldstein
16 The pointy end of the NAFLD iceberg: cirrhosis, portal hypertension, and liver failure, 182 Jonathon W. Schwake, Dawn M. Torres, and Stephen A. Harrison
17 Non-alcoholic fatty liver disease, hepatocellular cancer, and other cancers, 192 Janine Graham and Helen L. Reeves
18 NAFLD in Chinese and South Asian people, 206 Jia-Horng Kao, Deepak Amarapurkar, and Jian-Gao Fan
19 Non-alcoholic fatty liver disease in Japan, 217 Takeshi Okanoue, Kohichiroh Yasui, and Yoshito Itoh
20 Non-alcoholic fatty liver disease in South America and Hispanic people, 228 Helma Pinchemel Cotrim and Carla Daltro
21 Alcohol in non-alcoholic fatty liver disease: an oxymoron or a new standard of care?, 234 Achuthan Sourianarayanane, Srinivasan Dasarathy, and Arthur J. McCullough
22 Dietary factors in the pathogenesis and care of patients with fatty liver disease, 248 Giulio Marchesini, Rebecca Marzocchi, Anna S. Sasdelli, Cristiana Andruccioli, and Silvia Di Domizio
23 Metabolic factors and steatosis in patients with hepatitis B and C, 260 Francesco Negro
24 Drug therapy for NASH: insulin-sensitizing agents (metformin and thiazolidinediones), 271 Mohammad S. Siddiqui and Arun J. Sanyal
25 Hepatoprotectants against fatty liver disease: antioxidants, ursodeoxycholic acid, and herbal medicines, 284 Anne Catherine Bürgi and Jean-François Dufour
26 Lipid modifiers and NASH: statins, ezetimibe, fibrates, and other agents, 293 Giovanni Musso, Federica Molinaro, Elena Paschetta, Roberto Gambino, and Maurizio Cassader
Index, 308
Color plate section facing p86